论文本身:Melo, S. A., Luecke, L. B., Kahlert, C., Fernandez, A. F., Gammon, S. T., Kaye, J., . . . Kalluri, R. (2015). Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature. doi: 10.1038/nature14581
Thery大牛的评论:Thery, C. (2015). Cancer: Diagnosis by extracellular vesicles. Nature, 523(7559), 161-162. doi: 10.1038/nature14626
另一篇评论:Alderton, G. K. (2015). Diagnosis: Fishing for exosomes. Nat Rev Cancer, 15(8), 453. doi: 10.1038/nrc3990 这篇的题目和配图都很好玩。
相似的文献被提到有
Jakobsen, K. R. et al. J. Extracell. Vesicles 4, 26659(2015).
Madhavan, B. et al. Int. J. Cancer 136, 2616–2627(2015).
但是结果都没有GCP1好看,特异性太低,几乎没有临床指导意义,欢迎讨论!
Melo SA这个团队的相关文献有:
Melo, S. A., Sugimoto, H., O'Connell, J. T., Kato, N., Villanueva, A., Vidal, A., . . . Kalluri, R. (2014). Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis. Cancer Cell, 26(5), 707-721. doi: 10.1016/j.ccell.2014.09.005
Kahlert, C., Melo, S. A., Protopopov, A., Tang, J., Seth, S., Koch, M., . . . Kalluri, R. (2014). Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer. J Biol Chem, 289(7), 3869-3875. doi: 10.1074/jbc.C113.532267
Borges, F. T., Melo, S. A., Ozdemir, B. C., Kato, N., Revuelta, I., Miller, C. A., . . . Kalluri, R. (2013). TGF-beta1-containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis. J Am Soc Nephrol, 24(3), 385-392. doi: 10.1681/ASN.2012101031
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