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哎呀呀,这个问题我来回答简直太合适了。
只不过,我虽然做DC外泌体对内皮细胞的促炎作用,但是对DC外泌体的抗原呈递功能了解不多。
可以提供几篇参考文献给你:
1、Indirect activation of naïve CD4+ T cells by dendritic cell–derived exosomes. 2002, Nature Immunology.
2、Dendritic-cell exosomes cross-present Toll-like receptor-ligands and activate bystander dendritic cells. 2014, Cellular Immunology.
3、Mature dendritic cells pulsed with exosomes stimulate efficient cytotoxic T-lymphocyte responses and antitumour immunity. 2006, Immunology. |
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