外泌体之家 | 细胞外膜泡领域核心平台—exosomes & microvesicles—小膜泡大作用

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Extracellular vesicles的分类问题

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发表于 2015-3-29 23:07:02 | 只看该作者 回帖奖励 |倒序浏览 |阅读模式
exosomes?microvesicles?ectosomes?microparticles?shedding vesicles?

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发表于 2016-7-15 10:24:47 | 只看该作者
Extracellular vesicles encompass particles of different sizes, primarily exosomes (< 100 nm), which are
formed through a three-step process (invagination of the plasma membrane producing endocytic vesicles, inward budding of the endosomal membrane giving rise to multivesicular bodies and fusion of these bodies with the plasma membrane), and shedding microvesicles (up to 300 nm) which originate from the outward budding of cytoplasmic protrusions. They cargo a wide array of biomolecules, including microRNAs, proteins (more than 4000 different proteins and 700 different RNAs have been described so far), lipids and genetic material that they can horizontally transfer to target cells, thereby activating cytoprotective pathways as exemplified by the ability of cardiosphere-derived extracellular membrane vesicles to alter the phenotype of fibroblasts and endow them with angiogenic and cardioprotective properties
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板凳
发表于 2016-10-9 16:39:05 | 只看该作者
柳暗花明 发表于 2016-7-15 10:24
Extracellular vesicles encompass particles of different sizes, primarily exosomes (< 100 nm), which ...

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地板
发表于 2018-8-22 07:50:10 | 只看该作者
柳暗花明 发表于 2016-7-15 10:24
Extracellular vesicles encompass particles of different sizes, primarily exosomes (< 100 nm), which ...

请问一下,这是那篇文章的,谢谢。
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